Novel susceptibility gene for non-familial hypokalemic periodic paralysis

Novel susceptibility gene for non-familial hypokalemic periodic paralysis

Biotechin.Asia

Researchers from Taiwan recently reported a novel susceptibility gene for non-familial hypokalemic periodic paralysis. This study was published in Neurology.

microbiology-163470_1280 Credit: Pixabay

Familial periodic paralysis (FPP), both the hypo- and hyperkalemic variants, is a relatively rare inherited disorder but nevertheless, is known to most pediatricians. Hypokalemic/hyperkalemic periodic paralysis is a disorder that causes occasional episodes of muscle weakness and sometimes a lower/higher than normal level of potassium in the blood.

On the other hand, non-familial hypokalemic periodic paralysis linked with thyrotoxicosis (Thyrotoxic Periodic Paralysis or TPP) apparently has not been reported in the paediatric literature. Thyrotoxic periodic paralysis is a condition in which there are episodes of muscle weakness in people who have high levels of thyroid hormone in their blood (hyperthyroidism, thyrotoxicosis).

This disorder has been described most commonly in Asian males. A total of 2% of thyrotoxic patients in China and Japan were reported to have this complication, and…

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Author: Mahantesh Biradar

Mahantesh Biradar is a Graduate PhD researcher in Biomedical Science and passionate about Social Media Strategy | Biz Dev | Mindfulness | Yoga | Entrepreneurship. You can follow most of the updates online using the #MiB19

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